Macaenes and Macamides: The Unique Compounds Behind Maca’s Health Benefits
Posted by The Maca Team on 25th Jul 2025
If you’ve been exploring the world of superfoods, you’ve likely come across maca root, a nutrient-rich plant native to the Peruvian Andes that’s celebrated for its energy-boosting and hormone-balancing properties. But what exactly makes maca so special? Beyond its impressive vitamin and mineral content, maca contains two powerful types of compounds that are unique to the plant: macaenes and macamides.
These little-known yet potent phytochemicals are believed to be largely responsible for many of the adaptogenic and energizing effects maca is known for. In this post, we’ll dive into what macaenes and macamides are, what the science says about their effects, and how to choose maca products that preserve these valuable compounds.
What Are Macaenes and Macamides?
Macaenes and macamides are bioactive fatty acid compounds found almost exclusively in maca root. They are primarily formed during the drying and gelatinization process, which helps make maca more digestible while also unlocking some of its most important nutritional properties.
- Macaenes are a type of unsaturated fatty acid.
- Macamides are amide derivatives of those fatty acids.
Together, these compounds are thought to be unique markers of maca’s pharmacological activity. They don’t exist in high concentrations in other plants, which makes them a point of focus for researchers investigating maca’s effects on stamina, sexual health, and hormonal balance.
Why Are Macaenes and Macamides Important?
While maca contains a wide range of nutrients—including vitamin C, copper, iron, and plant sterols, it’s the presence of macaenes and macamides that sets it apart from other root vegetables and adaptogenic herbs. These compounds are believed to be behind many of the following benefits:
1. Energy and Endurance Support
Maca has long been used by indigenous Andean communities to boost stamina and physical performance, particularly at high altitudes. Some studies have shown that macamides may help enhance endurance by influencing the endocannabinoid system, an important regulatory system in the body involved in energy balance, mood, and motivation.
Research suggests that macamides interact with cannabinoid receptors in the body, potentially helping to regulate energy expenditure and reduce fatigue.
2. Hormonal Balance and Mood Support
One of the most popular uses for maca today is for supporting hormone balance, especially during periods of transition like menopause or andropause. Though maca does not contain hormones itself, macaenes and macamides appear to work as adaptogens, which are natural substances that help the body adapt to stress and maintain equilibrium.
Some studies indicate that these compounds may influence the hypothalamus and pituitary glands, which are central to hormone regulation. Macamides, in particular, may help modulate mood and reduce anxiety by supporting the body’s stress response.
3. Libido and Sexual Health
Perhaps the most well-known traditional use of maca is as a natural aphrodisiac. Modern research is beginning to support what ancient cultures already knew: maca can enhance libido and improve sexual function in both men and women.
Studies have found that macamides, in particular, may enhance sexual desire by improving energy levels, hormonal balance, and even sperm production in men. This has made maca a popular supplement for those looking to naturally support their reproductive health.
How Processing Affects Macaenes and Macamides
Not all maca products work the same. The content of macaenes and macamides can vary widely depending on how the maca is grown, processed, and stored.
- Gelatinized maca, which has been heated to remove starch, tends to have higher concentrations of these active compounds compared to raw maca.
- Proper drying at low temperatures helps preserve the delicate chemical structure of macaenes and macamides.
- Maca grown at high altitudes, like the Peruvian maca sold by The Maca Team, is thought to be richer in these compounds due to the plant's adaptation to harsh conditions.
That’s why it’s essential to choose high-quality maca products that are responsibly sourced and minimally processed. At The Maca Team, we only sell 100% organic, traditionally grown Peruvian maca, carefully processed to preserve its full spectrum of nutrients, including macaenes and macamides.
Choosing the Right Maca for Your Needs
Different types of maca - yellow, red, and black - may contain varying levels of macamides and macaenes, each offering slightly different benefits.
- Black maca is often preferred by men for energy, focus, and libido.
- Red maca is frequently recommended for women looking to support hormonal balance, especially during menopause.
- Yellow maca is the most versatile and is often used as a daily adaptogen for general wellness.
Regardless of the color, all our maca powders and capsules are tested to ensure they contain naturally high levels of active compounds, including macaenes and macamides.
The Bottom Line
Macaenes and macamides are what make maca truly unique. These powerful compounds are not found in significant amounts in any other food, and they may be the key reason maca root is such a valued adaptogen.
Whether you're seeking better energy, hormonal balance, or improved sexual health, choosing a maca product rich in these active compounds is essential. At The Maca Team, we’re committed to providing you with the highest-quality maca so you can enjoy all the benefits nature intended - no fillers, no shortcuts, just real Peruvian maca packed with macaenes and macamides.
If you have any questions for us about our maca, please don’t hesitate to Contact Us using our web form, or call us toll-free at 888-919-8616.
Enjoy the Day!